A number of &substituted 3, 11-dihydrodibenz [b, e][1, 4] oxazepines and 5, ll- dihydrodibenzo [b, e][1, 4] thiazepines have been prepared. When the 5-substituent is 3-[1- (2-hpdroxyethyl)-4-piperazinyl] propyl and a sitbstituent like C1 or CFa is in the 3, or 7 position, the compounds show antianxiety effects at lower duses and CXS depressant activity at higher doses. When the 5 substituent is a simple dialkylaminoalkyl group, then ...