The evolution of an amine dehydrogenase biocatalyst for the asymmetric production of chiral amines

MJ Abrahamson, JW Wong…

Index: Advanced Synthesis and Catalysis, , vol. 355, # 9 p. 1780 - 1786

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Citation Number: 29

Abstract

... Advanced Synthesis & Catalysis. ... ω-transaminase to produce sitagliptin.5,6 Biocatalysis is emerging as an essential tool in the asymmetric synthesis of chiral ... The production of chiral amines remains difficult through traditional chemical catalysis,3,14 and the direct amination of ...

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