Tetrahedron Letters

Cobalt (II) acetate promoted addition of acetoacetate to terminal olefins: A highly stereoselective synthesis of 5-alkyl-2-hydroxy 2 methyl-3-methoxycarbonyl …

J Iqbal, TKP Kumar, S Manogaran

Index: Iqbal, Javed; Kumar, T. K. Praveen; Manogaran, S. Tetrahedron Letters, 1989 , vol. 30, # 35 p. 4701 - 4702

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Citation Number: 14

Abstract

In a study directed towards the synthesis of tetrahydrofuranoid natural products, we required substituted dihydrofurans and envisioned that such a molecule can be synthesized by a metal promoted oxidative addition of acetoacetate to olefins. Manganese(lH) acetate pmmoted i addition of acetoacetate to activated olefins, has been shown to be a very efficient route to dihydrofurans and other cyclic organic molecules. The Manganese(lB) acetate pmmoted oxidative ...