Synthesis

Solid-phase synthesis of 3-hydroxy-2-methylenealkanoates and their derivatives using polymer-supported 2-(phenylseleno) propanoate

SR Sheng, FF Huang, SY Lin, XL Liu, X Huang

Index: Sheng, Shou-Ri; Huang, Fang-Fang; Lin, Shu-Ying; Liu, Xiao-Ling; Huang, Xian Synthesis, 2007 , # 9 p. 1373 - 1377

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Citation Number: 7

Abstract

Polymer-supported organic reagents and catalysts are frequently used in the preparation of organic molecules. The use of polymer-supported reagents means that excess reagents and byproducts can selectively be removed by simple filtration rather than by liquid-liquid extraction and chromatographic purification. In addition, polymer-supported reagents offer further advantages that include reaction of active intermediates by 'catch-and-release', selectivity and immobilization of toxic ...