Abstract A new type furo [2, 3-d] pyrimidine nucleoside conjugated with various carbohydrates was synthesized using Sonogashira coupling and 'click chemistry'. In the subsequent deprotection of the 4-toluoyl and acetyl groups with catalytic sodium methoxide in methanol, the furo [2, 3-d] pyrimidine rearranged to an opened ketone-type structure. Their structures were confirmed on the basis of spectroscopy.
