Synthesis of indanones via solid-supported [2+ 2+ 2] cyclotrimerization

RS Senaiar, JA Teske, DD Young…

Index: Senaiar, Ramesh S.; Teske, Jesse A.; Young, Douglas D.; Deiters, Alexander Journal of Organic Chemistry, 2007 , vol. 72, # 20 p. 7801 - 7804

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Citation Number: 37

Abstract

A new facile approach toward natural and unnatural indanones has been developed, featuring a solid-supported [2+ 2+ 2] cyclotrimerization as the key step. This strategy has been applied to the chemo-and regioselective assembly of indanone arrays and to the total synthesis of a recently isolated indanone marine natural product.