Journal of Heterocyclic Chemistry

… ??dimethyl substituted (unsubstituted)??4??aryl??3, 4??dihydropyrimidones (thiones) and corresponding bis??analogues in aqueous medium: Evaluation by green chemistry …

C Mukhopadhyay, A Datta

Index: Mukhopadhyay, Chhanda; Datta, Arup Journal of Heterocyclic Chemistry, 2010 , vol. 47, # 1 p. 136 - 146

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Citation Number: 8

Abstract

The actual driving force for the development of new catalysts for the structural motif-N, N 0- disubstituted (unsubstituted)-4-aryl-3, 4-dihydropyrimidones being a heterocyclic moiety of remarkable pharmacological importance [1] is to prepare compound libraries for screening in drug discoveries. The appropriately functionalized dihydropyrimidones (DHPMs) are very prominent as mitotic kinesin inhibitors, a1-adrenergic antagonists and potent hypertensive ...