Tetrahedron letters

Synthesis of optically active ring-A substituted tryptophans as IDO inhibitors

X Li, W Yin, PVVS Sarma, H Zhou, J Ma, JM Cook

Index: Tetrahedron Letters, , vol. 45, # 46 p. 8569 - 8573

Full Text: HTML

Citation Number: 35

Abstract

... Tetrahedron Letters. Volume 45, Issue 46, 8 November 2004, Pages 8569–8573. Cover image Cover image. ... Finally, the ethyl ester 44 was hydrolyzed to the corresponding carboxylic acid 45 with 1 N aq NaOH in ethanol in 50% yield (see Scheme 4). ...

 Related Synthetic Route
3-Aminopyridine Structure

462-08-8

3-Aminopyridine

~%

N-(4-Iodopyridin-3-yl)pivalamide Structure

113975-32-9

N-(4-Iodopyridi...

Pivaloyl chloride Structure

3282-30-2

Pivaloyl chloride

~%

N-(4-Iodopyridin-3-yl)pivalamide Structure

113975-32-9

N-(4-Iodopyridi...

4-chloro-1-iodo-2-nitrobenzene Structure

5446-05-9

4-chloro-1-iodo...

~%

6-Chloro-L-tryptophan Structure

33468-35-8

6-Chloro-L-tryp...

5-Chloro-2-iodoaniline Structure

6828-35-9

5-Chloro-2-iodo...

~%

6-Chloro-L-tryptophan Structure

33468-35-8

6-Chloro-L-tryp...

4-Chloro-2-nitroaniline Structure

89-63-4

4-Chloro-2-nitr...

~%

6-Chloro-L-tryptophan Structure

33468-35-8

6-Chloro-L-tryp...

N/A Structure

220906-11-6

N/A

~%

6-Chloro-L-tryptophan Structure

33468-35-8

6-Chloro-L-tryp...

6-chloro-3-(((2S,5R)-3,6-diethoxy-5-isopropyl-2,5-dihydropyrazin-2-yl)methyl)-2-(triethylsilyl)-1H-indole Structure

808145-70-2

6-chloro-3-(((2...

~%

6-Chloro-L-tryptophan Structure

33468-35-8

6-Chloro-L-tryp...

L-Valine Structure

72-18-4

L-Valine

Triphosgene Structure

32315-10-9

Triphosgene

~%

(4S)-4-Isopropyl-1,3-oxazolidine-2,5-dione Structure

24601-74-9

(4S)-4-Isopropy...

4-chloro-1-iodo-2-nitrobenzene Structure

5446-05-9

4-chloro-1-iodo...

~88%

5-Chloro-2-iodoaniline Structure

6828-35-9

5-Chloro-2-iodo...

4-Chloro-2-nitroaniline Structure

89-63-4

4-Chloro-2-nitr...

~%

5-Chloro-2-iodoaniline Structure

6828-35-9

5-Chloro-2-iodo...

4-Chloro-2-nitroaniline Structure

89-63-4

4-Chloro-2-nitr...

~94%

4-chloro-1-iodo-2-nitrobenzene Structure

5446-05-9

4-chloro-1-iodo...

N-(pyridin-3-yl)pivalamide Structure

70298-88-3

N-(pyridin-3-yl...

~%

4-Iodo-3-pyridinamine Structure

105752-11-2

4-Iodo-3-pyridi...

3-Aminopyridine Structure

462-08-8

3-Aminopyridine

~%

4-Iodo-3-pyridinamine Structure

105752-11-2

4-Iodo-3-pyridi...


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