A facile synthesis of 3??aryl??4??pyrazoleacetic acids and of their 4, 5??dihydro derivatives

…, GA Pinna, D Barlocco, G Cignarella

Index: Curzu; Pinna; Barlocco; Cignarella Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 2 p. 205 - 208

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Citation Number: 2

Abstract

Abstract N-1-Unsubstituted-3-aryl-4-pyrazoleacetic acids and their 4, 5-dihydro derivatives can conveniently be prepared by cyclization of 3-benzoyl-3-butenoic acids with hydrazine hydrate in acetic acid and subsequent treatment with bromine in acetic acid or, respectively, with diluted mineral acids.