The Lewis acid mediated transfer of an alkoxide ligand from the chiral ligand sphere of Ti- TADDOLate (1) to cyclic meso anhydrides to afford the corresponding hemiesters is described. By using this method a variety of structurally different anhydrides can be converted to isopropyl hemiesters with high enantioselectivities (enantiomer ratios up to 99: 1). We have also investigated Lewis acidic titanium complexes, which differ from 1 in the ...
![3-propan-2-yloxycarbonyl-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid Structure](https://image.chemsrc.com/caspic/377/29745-06-0.png)
