A convenient one pot synthesis of substituted 4??aminobenzopyrano [3, 4??c] pyridinones

DW Rangnekar, SV Dhamnaskar

Index: Rangnekar, D.W.,; Dhamnaskar, S.V., Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1767 - 1768

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Citation Number: 10

Abstract

Abstract A new synthesis of substituted 4-aminobenzopyrano [3, 4-c] pyridinones was achieved in one pot by the condensation of an o-hydroxyaraldehyde and a cyclic or acylic methyl ketone in the presence of ammonium acetate in refluxing ethanol followed by the treatment of malononitrile and subsequent hydrolysis with hydrochloric acid in situ.