Tetrahedron letters

Synthesis, evaluation and incorporation into liposomes of 4-functionalised-2, 5-diphenyloxazole derivatives for application in scintillation proximity assays

…, SJ Culliford, RZ Kozlowski, AJ Sutherland

Index: McCairn, Mark C.; Culliford, Steven J.; Kozlowski, Roland Z.; Sutherland, Andrew J. Tetrahedron Letters, 2004 , vol. 45, # 10 p. 2163 - 2166

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Citation Number: 4

Abstract

The preparation of a series of 4-functionalised-2, 5-diphenyloxazoles is described. The scintillating efficiency of each of these 'scintilipid'molecules has been evaluated in the presence of ionising radiation. Each 'scintilipid'has been assessed for the ability to assemble, with other lipids, into liposomes, under a variety of preparative conditions. Each liposomal preparation has been monitored for the ability to scintillate in the presence of ...