Abstract: A series of N-(imidazolidin-2-ylidene) hydrazones and N-(4, 5-dihydro-1H-imidazol- 2-yl)-N-methylhydrazones were prepared and examined for α1-, α2-adrenergic and imidazoline I1, I2 receptors binding affinities as well as cytotoxic activity against human tumor cell lines. Among the compounds tested, 2-naphthaldehyde N-(imidazolidin-2- ylidene) hydrazone (3e) exhibited a significant affinity for both α2-adrenergic and ...