Novel semicarbazones based 2, 5-disubstituted-1, 3, 4-oxadiazoles: One more step towards establishing four binding site pharmacophoric model hypothesis for …

…, R Deshmukh, R Veerasamy, AK Sharma…

Index: Rajak, Harish; Deshmukh, Ravitas; Veerasamy, Ravichandran; Sharma, Ajay Kumar; Mishra, Pradeep; Kharya, Murli Dhar Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 14 p. 4168 - 4172

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Citation Number: 35

Abstract

A series of novel N1-{5-[(naphthalene-2-yloxy) methyl]-1, 3, 4-oxadiazol-2-yl}-N4-(4- substitutedbenzaldehyde)-semicarbazone, N1-{5-[(naphthalene-2-yloxy) methyl]-1, 3, 4- oxadiazol-2-yl}-N4-[1-(4-substitutedphenyl) ethanone]-semicarbazone and N1-{5- [(naphthalene-2-yloxy) methyl]-1, 3, 4-oxadiazol-2-yl}-N4-[1-(4-substitutedphenyl)(phenyl) methanone]-semicarbazone were designed and synthesized on the basis of ...