Synthetic Communications

A General Synthesis of α-Substituted Acrylonitriles

RB Miller, BF Smith

Index: Miller,R.B.; Smith,B.F. Synthetic Communications, 1973 , vol. 3, p. 413 - 417

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Citation Number: 6

Abstract

Abstract During a study of synthetic approaches to naturally-occurring sesquiterpene lactones, a new synthesis of the α-methylene-y-butyrolactone group was developed1 and has subsequently been applied to the synthesis of various types of α-methylenecarbonyl compounds. 2 The synthetic scheme suggested that α-substituted acrylonitriles would also be available by this method.