Abstract Syntheses of 2, 3-dimethyl-4H-furo [3, 2-c] coumarin and 3-phenyl-4H-furo [3, 2-c] coumarin as angular furocoumarins were carried out through Williamson reaction of 4- hydroxycoumarin with α-haloketones followed by cyclization. Photooxygenation of the synthesized furocoumarin derivatives was performed and the photoproducts were isolated and characterized. The affinity of 2, 3-dimethyl-4H-furo [3, 2-c] coumarin towards DNA and ...