Abstract Split-and-mix libraries of resin-bound “tweezer” receptors have been prepared and screened to identify receptors for dye-labelled tripeptides. The receptors incorporate a diamidopyridine unit to serve as a specific recognition site for the CO 2 H group, leading to strong and selective receptors for peptide guests with a CO 2 H terminus. The role of the dye- label, attached to the peptide guest to allow visualisation of selective recognition events in ...