Chemistry–A European Journal

Iridium??Catalyzed Asymmetric Hydrogenation of N??Protected Indoles

A Baeza, A Pfaltz

Index: Baeza, Alejandro; Pfaltz, Andreas Chemistry - A European Journal, 2010 , vol. 16, # 7 p. 2036 - 2039

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Citation Number: 80

Abstract

Chiral indolines are common structures occurring in alkaloids and other natural or synthetic products that exhibit biological activity.[1] In addition, indolines with a stereogenic center at C-2 have been used as organocatalysts or chiral auxiliaries in asymmetric transformations.[2] Different methods have been developed to obtain such molecules in an enantioselective manner; however, only a few catalytic methods have been reported, most ...