Abstract A variety of novel functionalized phloroglucinol monoaryl ethers have been synthesized using a two-step procedure. Target ethers were synthesized by coupling electron-deficient aryl fluorides with 3, 5-dimethoxyphenol via nucleophilic aromatic substitution (SN Ar) in N-methylpyrrolidone and cesium carbonate. Subsequent boron tribromide-mediated demethylation gave a series of phloroglucinol monoaryl ethers in ...
