Synthesis of some Pyridothienopyrazolopyrimidopyrimidine and Mercaptomethylpyrazolopyrimidine derivatives

AM Kamal El-Dean, AM Elkhawaga…

Index: Kamal El-Dean; Elkhawaga; Radwan, Sh. M.; Ahmed Phosphorus, Sulfur and Silicon and the Related Elements, 2009 , vol. 184, # 8 p. 2034 - 2048

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Citation Number: 9

Abstract

Mercaptomethylpyrazolopyrimidine (2) was synthesized and reacted with ethyl chloroacetate to afford ethyl pyrazolpyrimidinylmethylmercapto acetate (3), which in turn was converted into the corresponding carbohydrazide 4. Carbohydrazide 4 reacts with a variety of reagents to give different pyrazolopyrimidines (5–12). Chloromethyl-pyrazolopyrimidine (1) reacts with chloropyridine to give compound 13, which was subjected in a series of ...

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Base-catalyzed one-pot tandem reaction: an effective strateg...

[Reddy, K Hemender; Reddy, A Panduranga; Veeranagaiah, V Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1992 , vol. 31, # 3 p. 163 - 166]