Tetrahedron letters

Selective functionalisation of hydrocarbons by nitric acid and aerobic oxidation catalysed by N-hydroxyphthalimide and iodine under mild conditions

…, F Recupero, C Gambarotti, C Punta, R Paganelli

Index: Minisci, Francesco; Recupero, Francesco; Gambarotti, Cristian; Punta, Carlo; Paganelli, Roberto Tetrahedron Letters, 2003 , vol. 44, # 36 p. 6919 - 6922

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Citation Number: 33

Abstract

Alkylbenzenes are selectively functionalised to the corresponding acetates by nitric aerobic oxidation catalysed by N-hydroxyphthalimide and iodine. With cyclohexane the oxidation leads to a mixture of cyclohexyl acetate and trans-2-iodocyclohexyl acetate. The mechanism is discussed.