Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system

E Bellale, M Naik, A Ambady, A Narayan…

Index: DAIICHI PHARMACEUTICAL CO., LTD Patent: US2003/92720 A1, 2003 ;

Full Text: HTML

Citation Number: 10

Abstract

... Interestingly, both electron-withdrawing and electron-donating groups were active. Furthermore, substituents at ortho, meta, and para positions were found to be equipotent from the limited set of electron-withdrawing and electron-donating groups explored (Table 2, 13–21). ...