Abstract A series of benzo-crown ethers containing the thiazole subcyclic moity have been synthesized. Reaction of 1, 2-bis (thioamidomethyloxy) benzene 2 with ethyl bromopyruvate in ethanol provided 1, 2-bis (thiazolyl) benzene 4 (80%) along with thiazole 5 (14%). Reduction of 4 with lithium aluminum hydride followed by mesylationbromination gave 7. Similar treatment of 5 with lithium aluminum hydride followed by bromination resulted in ...
![2-[2-(2-amino-2-oxoethoxy)phenoxy]acetamide Structure](https://image.chemsrc.com/caspic/203/82002-59-3.png)