Organic letters

Direct carbamoylation of aryl halides

RF Cunico, BC Maity

Index: Cunico, Robert F.; Maity, Bikash C. Organic Letters, 2002 , vol. 4, # 24 p. 4357 - 4359

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Citation Number: 49

Abstract

We now report that direct carbamoylation of aryl iodides, bromides, and chlorides can be carried out by employing carbamoylsilane 1 8 and one of several palladium catalysts (eq 1). A series of haloarenes have been examined under standard conditions involving a 1.0:1.1:0.02 molar ratio of ArX:1:Pd catalyst in toluene at 100 °C and results for aryl bromides are shown in Table 1. 9 Under catalysis by tetrakis(triphenylphosphine)palladium(0) (A), all unhindered ...