Discussion The strategy selected to achieve incorporation of the requisite dopamine- blocking activity into the 1-naphthylpiperazine nucleus is based on ideas promulgated some time ago by Ariens. lo Briefly, his approach involves modification of the structure of a receptor agonist, in this case dopamine, with a large lipophilic group on the amino position, which binds to the accessory binding site adjacent to the agonist binding site and ...
![2-bromo-1-[4-(2-chloroethyl)phenyl]ethanone Structure](https://image.chemsrc.com/caspic/249/69614-96-6.png)
