The synthetic estrogen diethylstilbestrol'(4,-4'-dihydroxy-a, a'-diethylstilbene) has achieved a position of importance as a therapeutic agent because of its availability and efficacy on oral administration, That significant therapeutic advantages might be offered by modification of the functional groups in the molecule as in the monomethyl led us to investigate other variants of a similar type. By procedures described in the experimental section, we have ...