A direct approach to the synthesis of famciclovir and penciclovir

BM Choudary, GR Geen, PM Kincey…

Index: Nucleosides and Nucleotides, , vol. 15, # 5 p. 981 - 994

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Citation Number: 18

Abstract

Page 1. NUCLEOSIDES & NUCLEOTIDES, 15(5), 981-994 (1996) A DIRECT APPROACH TO THE SYNTHESIS OF FAMCICLOVIR AND PENCICLOVIR ... The organic solvents were removed under vacuum until a reaction volume of 150ml was reached. ...

 Related Synthetic Route
[2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl]propanedioic acid dimethyl ester Structure

172529-93-0

[2-(2-Amino-6-c...

~%

2-[2-(2-amino-6-chloropurin-9-yl)ethyl]propane-1,3-diol Structure

172529-94-1

2-[2-(2-amino-6...

dimethyl 2-(2-(2-aminopurine-9-yl)ethyl)malonate Structure

122497-20-5

dimethyl 2-(2-(...

~54%

6-Deoxypenciclovir Structure

104227-86-3

6-Deoxypenciclovir

[2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl]propanedioic acid dimethyl ester Structure

172529-93-0

[2-(2-Amino-6-c...

~%

Famciclovir Structure

104227-87-4

Famciclovir

dimethyl 2-(2-(2-aminopurine-9-yl)ethyl)malonate Structure

122497-20-5

dimethyl 2-(2-(...

~%

Famciclovir Structure

104227-87-4

Famciclovir

[2-(2-Amino-6-chloro-9H-purin-9-yl)ethyl]propanedioic acid dimethyl ester Structure

172529-93-0

[2-(2-Amino-6-c...

~%

9-(4-Acetoxy-3-acetoxymethylbutyl)-2-amino-6-chloropurine Structure

97845-60-8

9-(4-Acetoxy-3-...


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