Palladium-catalyzed cross-coupling reactions of highly hindered, electron-rich phenol triflates and organostannanes

JM Saa, G Martorell, A Garcia-Raso

Index: Saa, Jose M.; Martorell, Gabriel; Garcia-Raso, Angel Journal of Organic Chemistry, 1992 , vol. 57, # 2 p. 678 - 685

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Citation Number: 104

Abstract

The palladium-catalyzed cross-coupling reaction of highly hindered, electron-rich phenol triflates and organostannanes (Stille reaction) has been studied in a systematic manner. The following are its salient features:(1) electron-rich phenol triflates require triphenylphosphine to undergo palladium-catalyzed cross-couplings;(2) in general, efficient reactions take place only when larger-than-usual amounts (10-1570) of palladium are employed. On the ...