Tetrahedron

Diastereoselective allylation and alkylation of optically active imines with metallic samarium and a catalytic amount of iodine

R Yanada, N Negoro, M Okaniwa, T Ibuka

Index: Yanada, Reiko; Negoro, Nobuyuki; Okaniwa, Masanori; Ibuka, Toshiro Tetrahedron, 1999 , vol. 55, # 49 p. 13947 - 13956

Full Text: HTML

Citation Number: 41

Abstract

Barbier-type allylation and alkylation of optically active imines such as N-benzylidenevalinol methyl ether was performed with metallic samarium, a catalytic amount of iodine, and allyl or alkyl halides. This reaction proceeded in a highly diastereoselective manner in THF at room temperature.