Synthesis of Chiral 2??Hydroxy??1??methylpropanoates by Rhodium??Catalyzed Stereoselective Hydrogenation of α??(Hydroxymethyl)??acrylate Derivatives

J Holz, B Schäffner, O Zayas…

Index: Advanced Synthesis and Catalysis, , vol. 350, # 16 p. 2533 - 2543

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Citation Number: 19

Abstract

... Advanced Synthesis & Catalysis. ... The synthesis of chiral 3-hydroxy-2-methylpropanoic acid esters (eg, “Roche ester” 3a) based on the ... 9 G. Shang, X. Zhang, Phospholes, Phospholenes, Phospholanes and Phosphinanes, in: Phosphorus Ligands in Asymmetric Catalysis, (Ed.: A ...