Umpolung Reactivity of Difluoroenol Silyl Ethers with Amines and Amino Alcohols. Application to the Synthesis of Enantiopure α-Difluoromethyl Amines and Amino …

F Huguenot, A Billac, T Brigaud…

Index: Jin, Fuqiang; Jiang, Biao; Xu, Yuanyao Tetrahedron Letters, 1992 , vol. 33, # 9 p. 1221 - 1224

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Citation Number: 21

Abstract

... Volume: Page: ... were essentially used as key intermediates in the synthesis of polyfluorinated β-enaminoketones and heterocycles, 9 via an ... Addition of phenylglycinol and a catalytic amount of pyridinium p-toluenesulfonate, and heating to reflux afforded the ...