Tetrahedron Letters

An efficient synthesis of indoloquinoline alkaloid—neocryptolepine (cryptotackieine)

PT Parvatkar, SG Tilve

Index: Parvatkar, Prakash T.; Tilve, Santosh G. Tetrahedron Letters, 2011 , vol. 52, # 49 p. 6594 - 6596

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Citation Number: 15

Abstract

Plants are still the important resources for the discovery of new drugs. The roots of the West African plant Cryptolepis sanguinolenta have long been used by Ghanaian healers to treat a variety of disorders such as infectious diseases, amebiasis, and fever including malaria 1, 2 and 3 and have proved to be a rich source of indoloquinoline alkaloids. Neocryptolepine 1 (also named cryptotackieine) is one of the thirteen characterized alkaloids isolated from C. ...