Tetrahedron Letters

A protein–rhodium complex as an efficient catalyst for two-phase olefin hydroformylation

M Marchetti, G Mangano, S Paganelli, C Botteghi

Index: Marchetti; Mangano; Paganelli; Botteghi Tetrahedron Letters, 2000 , vol. 41, # 19 p. 3717 - 3720

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Citation Number: 44

Abstract

A highly efficient and chemoselective biphasic hydroformylation of olefins was accomplished using water soluble complexes formed by the interaction between Rh (CO) 2 (acac) and human serum albumin (HSA), a readily available water soluble protein. A new type of shape- selectivity was observed in the hydroformylation of sterically hindered olefins.