Total Synthesis of (−)-Martinellic Acid via Radical Addition− Cyclization− Elimination Reaction

…, M Miyata, DJ Procter, D Sucunza, T Naito

Index: Hewson, Alan T.; Hughes, Kevin; Richardson, Steward K.; Sharpe, David A.; Wadsworth, Alan H. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 6 p. 1565 - 1569

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Citation Number: 46

Abstract

... 21) oxime−alkene cyclizations have received little attention.(22) Treatment of 5b with SmI 2 in THF with t-BuOH as a ... the acidic conditions (entry 1). The selective deprotection of the carbonate group proceeded smoothly in the presence of K 2 CO 3 (1.5 equiv) in MeOH:H 2 O ...