General synthetic system for 1, 2, 5-thiadiazoles

LM Weinstock, P Davis, B Handelsman…

Index: Weinstock,L.M. et al. Journal of Organic Chemistry, 1967 , vol. 32, p. 2823 - 2829

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Citation Number: 179

Abstract

A general model for the synthesis of 1, 2, 5-thiadiszoles is described in terms of an acyclic NCCN grouping in which the NC! functions are varied over the oxidation levels of amine, imine, cyanide, and oxime. Aliphatic compounds containing these functionalities in any combination are converted to appropriately substituted 1, 2, 5-thiadiazoles by react> ion with sulfur monochloride or sulfur dichloride. Acylic compounds which are applicable in this ...