Abstract: An environmentally benign approach for the synthesis of 2-aryl-3H-quinazolin-4- ones employing sodium perborate (SPB) as catalyst is described. SPB in water and acetone system is proved as selective catalyst of hydration for cyanides. The rate enhancement and high yield is attributed to the coupling of suitable catalyst with the solvent system. The key step is the microwave prompted reaction sequence combining 2-aminobenzonitrile and ...
