Tetrahedron

Palladium-catalyzed carbonylative synthesis of N-(2-cyanoaryl) benzamides and sequential synthesis of quinazolinones

XF Wu, S Oschatz, M Sharif, M Beller, P Langer

Index: Wu, Xiao-Feng; Oschatz, Stefan; Sharif, Muhammad; Beller, Matthias; Langer, Peter Tetrahedron, 2014 , vol. 70, # 1 p. 23 - 29

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Citation Number: 24

Abstract

Abstract A convenient procedure for the synthesis of N-(2-cyanoaryl) benzamides has been developed. Using aryl bromides and 2-aminobenzonitriles as the substrates, Mo (CO) 6 as the CO source, the desired amides were produced in good yields. Quinazolinones were produced in good yields in a sequential manner as well.