Synlett

Selective 1, 4-reduction of α, β-unsaturated carbonyl compounds by combined use of bis (1, 3-diketonato) cobalt (II) complex and diisobutylaluminum hydride

T Ikeno, T Kimura, Y Ohtsuka, T Yamada

Index: Ikeno, Taketo; Kimura, Tomomi; Ohtsuka, Yuhki; Yamada, Tohru Synlett, 1999 , # 1 p. 96 - 98

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Citation Number: 13

Abstract

Abstract: By the combined use of Co (acac) 2 with DIBAL, various a, b-unsaturated carbonyl compounds such as enones, a, b-unsaturated carboxylates and carboxamides were selectively reduced in a 1, 4-manner to obtain the corresponding 1, 4-reduced products in good-to-high yields. Key words: 1, 4-reduction, diisobutylaluminum hydride, cobalt hydride, bis (acetylacetonato) cobalt (II) complex, α, β-unsaturated carbonyl compound