Synthesis and antiviral activity of novel pyrazole amides containing α??aminophosphonate moiety

L Wu, B Song, PS Bhadury, S Yang…

Index: Wu, Lintao; Song, Baoan; Bhadury, Pinaki S.; Yang, Song; Hu, Deyu; Jin, Linhong Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 2 p. 389 - 396

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Citation Number: 12

Abstract

Abstract A series of novel pyrazole amides J1, J2, J3, J4, J5, J6, J7, J8, J9, J10, J11, J12, J13, J14, J15 containing an α-aminophosphonate moiety were synthesized and subsequently characterized by spectral (IR, 1 H-, 13 C-, 31 P-, and 19 F-NMR) data and elemental analysis. The racemic sample of J1 was further separated into its enantiomers under normal-phase condition on two immobilized polysaccharide-based chiral stationary ...