In an extension of very recently published studies on successful imidazole replacements in some series of histamine H3 receptor antagonists, we report on a new class of lipophilic nonimidazole antagonist having an aliphatic tertiary amino moiety connected to a benzyl template substituted in the 4-position by a phenoxymethyl group. The structural modifications were performed with the intention to avoid possible negative side effects ...
[Ridd, John H.; Yousaf, Taher I.; Rose, John B. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1988 , p. 1729 - 1734]
