Tetrahedron: Asymmetry

Lipase mediated preparation of the enantiomers of 3, 3, 3-trifluoro-2-methylpropanoic acid

P Beier, AMZ Slawin, D O'Hagan

Index: Beier, Petr; Z. Slawin, Alexandra M.; O'Hagan, David Tetrahedron Asymmetry, 2004 , vol. 15, # 16 p. 2447 - 2449

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Citation Number: 2

Abstract

... 6]; P. Beier, D. O'Hagan; J. Chem. Soc., Chem. Commun. (2002), p. 1680. ... 19 F NMR (282 MHz, CDCl 3 ; CFCl 3 ): δ −69.9 (d, J = 8.6 Hz). 13 C NMR (75 MHz, CDCl 3 ): δ 165.6, 142.4, 128.8, 127.6, 126.0, 125.6 (q, J = 280 Hz), 49.2, 46.3 (q, J = 28 Hz), 21.5, 11.0. MS (EI): m/z (rel int.) = 245 [M] + (60), 230 [M−Me] + (50), 120 (20), 106 (100), 105 (40), 77 (30). MS (ESI): m/z = 244 [M−H] −. [16]; (a) KH Engel; Tetrahedron: Asymmetry, 2 (1991), p. 165. ...