The synthesis of methyl α-(trifluoromethyl) acrylate (MTFMA) has been carried out in three steps starting from commercially available 3, 3, 3.-trifluoropropene; this route involving the cobalt-catalyzed carbonylation of 2-bromo-3, 3, 3-trifluoropropene (2-Br-TFP) under very mild reaction conditions, gave only about 30% yield of the desired methyl ester. 2- (Trifluoromethyl) propanal, available in 90% yield by rhodium catalyzed hydroformylation ...
