Macrocyclic inhibitors of β-secretase: functional activity in an animal model

SJ Stachel, CA Coburn…

Index: Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6147 - 6150

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Citation Number: 86

Abstract

... Journal of Medicinal Chemistry. ... Department of Medicinal Chemistry, Biological Chemistry, Molecular Systems and Structural Biology Merck Research Laboratories, Post Office Box 4, West Point, Pennsylvania 19486. J. Med. Chem. ...

Macrocyclic inhibitors of β-secretase: functional activity i...

[Stachel, Shawn J.; Coburn, Craig A.; Sankaranarayanan, Sethu; Price, Eric A.; Pietrak, Beth L.; Huang, Qian; Lineberger, Janet; Espeseth, Amy S.; Jin, Lixia; Ellis, Joan; Holloway, M. Katharine; Munshi, Sanjeev; Allison, Timothy; Hazuda, Daria; Simon, Adam J.; Graham, Samuel L.; Vacca, Joseph P. Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6147 - 6150]

Potential organ or tumor imaging agents. 11. Radioiodinated ...

[Journal of Medicinal Chemistry, , vol. 16, p. 684 - 687]