Biochemical investigation of pikromycin biosynthesis employing native penta-and hexaketide chain elongation intermediates

CC Aldrich, BJ Beck, RA Fecik…

Index: Mohr, Peter; Waespe-Sarcevic, Nada; Tamm, Christoph; Gawronska, Krystyna; Gawronsky, Jacek K. Helvetica Chimica Acta, 1983 , vol. 66, # 8 p. 2501 - 2511

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Citation Number: 41

Abstract

... Volume: Page: ... 14-17 Specifically, the calculated k cat values for extension and lactonization of diketide substrates by the terminal Pik PKS ... with hydrofluoric acid in acetonitrile provided the pentaketide NAC thioester 5 in only five steps from 8. The convergent ...