Tetrahedron: Asymmetry

Stereoselective synthesis of (−)-(1R, 2S)-2-aminocyclobutane-1-carboxylic acid, a conformationally constrained β-amino acid

M Martı́n-Vilà, C Minguillón, RM Ortuño

Index: Martin-Vila, Marta; Minguillon, Cristina; Ortuno, Rosa M. Tetrahedron Asymmetry, 1998 , vol. 9, # 24 p. 4291 - 4294

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Citation Number: 40

Abstract

The title compound as well as some derivatives have been synthesized for the first time in optically active form by means of a chemoenzymatic transformation used to induce asymmetry in achiral precursors. The enantio-and diastereomeric purity has been ...