Tetrahedron letters

Practical method for synthesis of optically pure propargylic alcohols

T Ito, S Okamoto, F Sato

Index: Ito, Takayori; Okamoto, Sentaro; Sato, Fumie Tetrahedron Letters, 1989 , vol. 30, # 50 p. 7083 - 7086

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Citation Number: 23

Abstract

Abstract Highly efficient practical method for synthesis of optically pure propargylic alcohols is described which involves the synthesis of chiral γ-iodo allylic alcohols by the Sharpless kinetic resolution of secondary γ-hetero substituted allylic alcohols and their 1, 2- dehydrohalogenation reaction.

~74%

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