Aminocatalysis has undergone an intense development over the last decade, mainly due to its potential for simplifying and improving many different reactions and procedures.[1] Until now, proline-derived catalysts account for most applications in this field. These species are generally derived from natural l-proline or trans 4-hydroxyproline, and therefore the functionalization pattern of the pyrrolidine ring appears somehow restricted to a 2-or 2, 4- ...
