Palladium??Catalyzed 2??Pyridylmethyl Transfer from 2??(2??Pyridyl) ethanol Derivatives to Organic Halides by Chelation??Assisted Cleavage of Unstrained C sp 3 C sp …

T Niwa, H Yorimitsu, K Oshima

Index: Niwa, Takashi; Yorimitsu, Hideki; Oshima, Koichiro Angewandte Chemie - International Edition, 2007 , vol. 46, # 15 p. 2643 - 2645

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Citation Number: 78

Abstract

Transition-metal-catalyzed cleavage of carbon–carbon bonds is not only scientifically challenging but also potentially useful in organic synthesis.[1] Among the bond-breaking reactions, the cleavage of unstrained carbon–carbon bonds ranks as one of the most difficult processes because of the lack of sufficient strain energy as a driving force. Assistance by chelation is promising for the metal-mediated cleavage of such unstrained carbon–carbon ...