Evaluation of a 3-amino-8-azabicyclo [3.2. 1] octane replacement in the CCR5 antagonist maraviroc

…, T Baldinger, J Wanner, A Jekle, G Heilek, C Ji…

Index: Lemoine, Remy C.; Petersen, Ann C.; Setti, Lina; Baldinger, Thomas; Wanner, Jutta; Jekle, Andreas; Heilek, Gabrielle; deRosier, Andre; Ji, Changhua; Rotstein, David M. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 5 p. 1674 - 1676

Full Text: HTML

Citation Number: 7

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The bicyclic 5-amino-3-azabicyclo[3.3.0]octanes were shown to be effective replacements for the 3-amino-8-azabicyclo[3.2.1]octane found in the CCR5 antagonist maraviroc. ... The bicyclic 5-amino-3-azabicyclo[3.3.0]octanes were shown to be effective replacements for the 3- ...