An Efficient and Environmentally Friendly Procedure for the Synthesis of Some Novel 8-Benzylidene-4-phenyl-3, 4, 5, 6, 7, 8-hexahydro-1H-quinazolin-2-ones/thiones …

M Ghashang, SS Mansoor…

Index: Ghashang, Majid; Mansoor, Syed Sheik; Aswin, Krishnamoorthy Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 11 p. 3289 - 3294

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Abstract

Abstract An efficient method for the preparation of 8-benzylidene-4-phenyl-3, 4, 5, 6, 7, 8- hexahydro-1H-quinazolin-2-ones/thiones from the reaction of aromatic aldehydes with cyclohexanone and urea or thiourea in the presence of Tetrabutylammonium hexatungstate,, as an efficient, inexpensive catalyst under thermal and solvent-free conditions has been developed. Good yields, short reaction times, straightforward workup, ...